Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
نویسندگان
چکیده
منابع مشابه
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.
Here, we present a large (n = 107,207) genome-wide association study (GWAS) of general cognitive ability ("g"), further enhanced by combining results with a large-scale GWAS of educational attainment. We identified 70 independent genomic loci associated with general cognitive ability. Results showed significant enrichment for genes causing Mendelian disorders with an intellectual disability phe...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2021
ISSN: 0893-133X,1740-634X
DOI: 10.1038/s41386-021-01023-4